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Fmo3 (NM_008030) Mouse Recombinant Protein

Product Specifications

Background

Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thrombus formation.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse flavin containing monooxygenase 3 (Fmo3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

AW111792

Gene ID

14262

UniProt

P97501, Q3UEN4, Q8C7J1

Accession Number mRNA

NM_008030

Chromosomal Location

1 70.34 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

61 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Fmo3

Species

Mouse

Protein ID

NP_032056

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/14262

Uniprot URL

https://www.uniprot.org/uniprot/P97501

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_008030

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_032056

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