Bace2 (NM_019517) Mouse Recombinant Protein
Product Specifications
Background
This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein undergoes proteolytic processing to generate an active endopeptidase enzyme. This transmembrane protease catalyzes the proteolysis of amyloid precursor protein to produce amyloid beta peptide. Mice lacking the encoded product exhibit increased pancreatic beta cell mass and improved glucose tolerance due to increased insulin secretion. [provided by RefSeq, Jul 2016]
Synonyms
1110059C24Rik; A; AEPLC; AI850424; AL; ALP56; ARP1; AS; ASP1; ASP21; BAE; BAE2; CDA1; CDA13; CEA; CEAP1; DRAP
Gene ID
56175
UniProt
Q9JL18, A0A0R4J0I8
Accession Number mRNA
NM_019517
Chromosomal Location
16 C4
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
56.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Bace2
Species
Mouse
Protein ID
NP_062390
Overview
Purified recombinant protein of Mouse beta-site APP-cleaving enzyme 2 (Bace2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/56175
Uniprot URL
https://www.uniprot.org/uniprot/Q9JL18
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_019517
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_062390
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