Il12rb1 (NM_008353) Mouse Recombinant Protein
Product Specifications
Background
Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse interleukin 12 receptor, beta 1 (Il12rb1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
CD212; IL-12R[b]
Gene ID
16161
UniProt
Q60837
Accession Number mRNA
NM_008353
Chromosomal Location
8 34.21 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
82.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Il12rb1
Species
Mouse
Protein ID
NP_032379
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/16161
Uniprot URL
https://www.uniprot.org/uniprot/Q60837
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_008353
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_032379
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