Il12rb1 (NM_008353) Mouse Recombinant Protein

Product Specifications

Background

Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse interleukin 12 receptor, beta 1 (Il12rb1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

CD212; IL-12R[b]

Gene ID

16161

UniProt

Q60837

Accession Number mRNA

NM_008353

Chromosomal Location

8 34.21 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

82.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.