Asic2 (NM_007384) Mouse Recombinant Protein
Product Specifications
Background
Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li (+) and K (+) . Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse acid-sensing (proton-gated) ion channel 2 (Asic2), transcript variant MDEG2, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
Accn1; ACIC2; BNaC1; BNaC1a; BNC1; Mdeg
Gene ID
11418
UniProt
Q925H0, B2RRQ1
Accession Number mRNA
NM_007384
Chromosomal Location
11 48.43 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
63.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Asic2
Species
Mouse
Protein ID
NP_031410
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/11418
Uniprot URL
https://www.uniprot.org/uniprot/Q925H0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007384
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_031410
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