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Asic2 (NM_007384) Mouse Recombinant Protein

Product Specifications

Background

Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li (+) and K (+) . Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse acid-sensing (proton-gated) ion channel 2 (Asic2), transcript variant MDEG2, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

Accn1; ACIC2; BNaC1; BNaC1a; BNC1; Mdeg

Gene ID

11418

UniProt

Q925H0, B2RRQ1

Accession Number mRNA

NM_007384

Chromosomal Location

11 48.43 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

63.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Asic2

Species

Mouse

Protein ID

NP_031410

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/11418

Uniprot URL

https://www.uniprot.org/uniprot/Q925H0

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_007384

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_031410

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