Rnf166 (NM_001033142) Mouse Recombinant Protein
Product Specifications
Background
E3 ubiquitin-protein ligase that promotes the ubiquitination of different substrates. In turn, participates in different biological processes including interferon production or autophagy. Plays a role in the activation of RNA virus-induced interferon-beta production by promoting the ubiquitination of TRAF3 and TRAF6. Plays also a role in the early recruitment of autophagy adapters to bacteria. Mediates 'Lys-29' and 'Lys-33'-linked ubiquitination of SQSTM1 leading to xenophagic targeting of bacteria and inhibition of their replication.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse ring finger protein 166 (Rnf166), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
1110031E24Rik; AW555115; Zfp313l
Gene ID
68718
UniProt
Q3U9F6, A2RS02
Accession Number mRNA
NM_001033142
Chromosomal Location
8 E1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
26.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Rnf166
Species
Mouse
Protein ID
NP_001028314
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/68718
Uniprot URL
https://www.uniprot.org/uniprot/Q3U9F6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001033142
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001028314
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