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Setd6 (NM_001035123) Mouse Recombinant Protein

Product Specifications

Background

Protein-lysine N-methyltransferase. Monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity. Monomethylates 'Lys-8' of H2AZ (H2AZK8me1) (By similarity) . Required for the maintenance of embryonic stem cell self-renewal (PubMed:23324626) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse SET domain containing 6 (Setd6), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

0610039J04Rik; 3110004G14Rik; AI413388; C76402

Gene ID

66083

UniProt

Q9CWY3

Accession Number mRNA

NM_001035123

Chromosomal Location

8 D1

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

53.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Setd6

Species

Mouse

Protein ID

NP_001030295

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/66083

Uniprot URL

https://www.uniprot.org/uniprot/Q9CWY3

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001035123

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001030295

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