Setd6 (NM_001035123) Mouse Recombinant Protein
Product Specifications
Background
Protein-lysine N-methyltransferase. Monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity. Monomethylates 'Lys-8' of H2AZ (H2AZK8me1) (By similarity) . Required for the maintenance of embryonic stem cell self-renewal (PubMed:23324626) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse SET domain containing 6 (Setd6), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
0610039J04Rik; 3110004G14Rik; AI413388; C76402
Gene ID
66083
UniProt
Q9CWY3
Accession Number mRNA
NM_001035123
Chromosomal Location
8 D1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
53.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Setd6
Species
Mouse
Protein ID
NP_001030295
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/66083
Uniprot URL
https://www.uniprot.org/uniprot/Q9CWY3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001035123
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001030295
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