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Ptprr (NM_011217) Mouse Recombinant Protein

Product Specifications

Background

Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus. Isoform gamma may have a role in patterning and cellular proliferation of skeletal elements in the precartilaginous/cartilaginous skeleton.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse protein tyrosine phosphatase, receptor type, R (Ptprr), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

Gmcp1; mPTP213; PTP-SL; PTPBR7; RPTPRR

Gene ID

19279

UniProt

Q62132, Q5U1U6, Q8CEI8

Accession Number mRNA

NM_011217

Chromosomal Location

10 D2

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

74.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Ptprr

Species

Mouse

Protein ID

NP_035347

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/19279

Uniprot URL

https://www.uniprot.org/uniprot/Q62132

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_011217

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_035347

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