Ptprr (NM_011217) Mouse Recombinant Protein
Product Specifications
Background
Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus. Isoform gamma may have a role in patterning and cellular proliferation of skeletal elements in the precartilaginous/cartilaginous skeleton.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse protein tyrosine phosphatase, receptor type, R (Ptprr), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
Gmcp1; mPTP213; PTP-SL; PTPBR7; RPTPRR
Gene ID
19279
UniProt
Q62132, Q5U1U6, Q8CEI8
Accession Number mRNA
NM_011217
Chromosomal Location
10 D2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
74.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Ptprr
Species
Mouse
Protein ID
NP_035347
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/19279
Uniprot URL
https://www.uniprot.org/uniprot/Q62132
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_011217
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_035347
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