Lrrfip1 (NM_001111311) Mouse Recombinant Protein
Product Specifications
Background
Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA (By similarity) . Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
AU024550; Fliiap1
Gene ID
16978
UniProt
Q3UZ39
Accession Number mRNA
NM_001111311
Chromosomal Location
1 D
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
79.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Lrrfip1
Species
Mouse
Protein ID
NP_001104781
Overview
Purified recombinant protein of Mouse leucine rich repeat (in FLII) interacting protein 1 (Lrrfip1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/16978
Uniprot URL
https://www.uniprot.org/uniprot/Q3UZ39
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001111311
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001104781
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