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Psmc6 (NM_025959) Mouse Recombinant Protein

Product Specifications

Background

Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC6 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse proteasome (prosome, macropain) 26S subunit, ATPase, 6 (Psmc6), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

2300001E01Rik; AI451058

Gene ID

67089

UniProt

P62334, Q14AQ1

Accession Number mRNA

NM_025959

Chromosomal Location

14 C1

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

44.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Psmc6

Species

Mouse

Protein ID

NP_080235

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/67089

Uniprot URL

https://www.uniprot.org/uniprot/P62334

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_025959

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_080235

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