Rbbp4 (NM_009030) Mouse Recombinant Protein
Product Specifications
Background
Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse retinoblastoma binding protein 4, chromatin remodeling factor (Rbbp4), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
MRbAp48; RBAP48
Gene ID
19646
UniProt
Q60972
Accession Number mRNA
NM_009030
Chromosomal Location
4 D2.2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
48.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Rbbp4
Species
Mouse
Protein ID
NP_033056
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/19646
Uniprot URL
https://www.uniprot.org/uniprot/Q60972
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_009030
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_033056
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