Pcbp2 (NM_001103165) Mouse Recombinant Protein

Product Specifications

Background

Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly (rC) -binding protein. Binds also poly (rU) . Negatively regulates cellular antiviral responses mediated by MAVS signaling. It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitinationa and degradation (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse poly (rC) binding protein 2 (Pcbp2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

AlphaCP-2; AW412548; Hnrpx

Gene ID

18521

UniProt

Q61990, Q3TT81

Accession Number mRNA

NM_001103165

Chromosomal Location

15 57.61 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

38.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.