Siglec1 (NM_011426) Mouse Recombinant Protein
Product Specifications
Background
Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells (By similarity) . Preferentially binds to alpha-2,3-linked sialic acid. Binds to SPN/CD43 on T-cells. May play a role in hematopoiesis. May act as a counter-receptor for CLEC10A in lymph node.[UniProtKB/Swiss-Prot Function]
Synonyms
Cd169; Siglec-1; Sn
Gene ID
20612
UniProt
Q62230, G3X8X6
Accession Number mRNA
NM_011426
Chromosomal Location
2 63.26 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
184 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Siglec1
Species
Mouse
Protein ID
NP_035556
Overview
Purified recombinant protein of Mouse sialic acid binding Ig-like lectin 1, sialoadhesin (Siglec1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/20612
Uniprot URL
https://www.uniprot.org/uniprot/Q62230
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_011426
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_035556
Curated Selection
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