Siglec1 (NM_011426) Mouse Recombinant Protein

Product Specifications

Background

Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells (By similarity) . Preferentially binds to alpha-2,3-linked sialic acid. Binds to SPN/CD43 on T-cells. May play a role in hematopoiesis. May act as a counter-receptor for CLEC10A in lymph node.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse sialic acid binding Ig-like lectin 1, sialoadhesin (Siglec1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

Cd169; Siglec-1; Sn

Gene ID

20612

UniProt

Q62230, G3X8X6

Accession Number mRNA

NM_011426

Chromosomal Location

2 63.26 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

184 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.