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Vash1 (NM_177354) Mouse Recombinant Protein

Product Specifications

Background

Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function (PubMed:29146868) . Acts as an angiogenesis inhibitor: inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis (PubMed:19204325) . This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse vasohibin 1 (Vash1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

AI834978; D930046M13Rik; G630009D10Rik

Gene ID

238328

UniProt

Q8C1W1

Accession Number mRNA

NM_177354

Chromosomal Location

12 D2

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

42.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Vash1

Species

Mouse

Protein ID

NP_796328

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/238328

Uniprot URL

https://www.uniprot.org/uniprot/Q8C1W1

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_177354

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_796328

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