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Dlg2 (NM_011807) Mouse Recombinant Protein

Product Specifications

Background

Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse discs large MAGUK scaffold protein 2 (Dlg2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

A330103J02Rik; B230218P12Rik; B330007M19Rik; Dlgh2; Gm1197; Gm21505; PSD93

Gene ID

23859

UniProt

Q91XM9

Accession Number mRNA

NM_011807

Chromosomal Location

7 51.07 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

94.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Dlg2

Species

Mouse

Protein ID

NP_035937

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/23859

Uniprot URL

https://www.uniprot.org/uniprot/Q91XM9

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_011807

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_035937

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