Six5 (NM_011383) Mouse Recombinant Protein
Selected Variant
PM43251M5
Size: 20 µg
Product Specifications
Background
Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5'-GGTGTCAG-3' motif present in the ARE regulatory element of ATP1A1. Binds a 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the myogenin promoter, and in the IGFBP5 promoter (By similarity) . Thought to be regulated by association with Dach and Eya proteins, and seems to be coactivated by EYA1, EYA2 and EYA3.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse sine oculis-related homeobox 5 (Six5), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
Dmahp; MDMAHP; TrexBF
Gene ID
20475
UniProt
P70178
Accession Number mRNA
NM_011383
Chromosomal Location
7 9.46 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
73.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Six5
Species
Mouse
Protein ID
NP_035513
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/20475
Uniprot URL
https://www.uniprot.org/uniprot/P70178
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_011383
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_035513
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