Ripor2 (NM_029679) Mouse Recombinant Protein

Acts as an inhibitor of the small GTPase RHOA and plays several roles in the regulation of myoblast and hair cell differentiation, lymphocyte T proliferation and neutrophil polarization (PubMed:25588844, PubMed:27269051) . Plays a role in fetal mononuclear myoblast differentiation by promoting filopodia and myotube formation (PubMed:17150207) . Maintains naive T lymphocytes in a quiescent state and prevents chemokine-induced T lymphocyte responses, such as cell adhesion, polarization and migration (By similarity) . Involved also in the regulation of neutrophil polarization, chemotaxis and adhesion (PubMed:25588844) . Required for normal development of inner and outer hair cell stereocilia within the cochlea of the inner ear (PubMed:27269051) . Plays a role for maintaining the structural organization of the basal domain of stereocilia (PubMed:27269051) . Involved in mechanosensory hair cell function (PubMed:27269051) . Required for normal hearing (PubMed:27269051) .[UniProtKB/Swiss-Prot Function]

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Purified recombinant protein of Mouse RHO family interacting cell polarization regulator 2 (Ripor2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug