Xpnpep3 (NM_177310) Mouse Recombinant Protein
Product Specifications
Background
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Leu-Pro-Ala. Also shows low activity towards peptides with Ala or Ser at the P1 position. Promotes TNFRSF1B-mediated phosphorylation of MAPK8/JNK1 and MAPK9/JNK2, suggesting a function as an adapter protein for TNFRSF1B; the effect is independent of XPNPEP3 peptidase activity. May inhibit apoptotic cell death induced via TNF-TNFRSF1B signaling.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse X-prolyl aminopeptidase 3, mitochondrial (Xpnpep3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
APP3; E430012M05Rik
Gene ID
321003
UniProt
B7ZMP1
Accession Number mRNA
NM_177310
Chromosomal Location
15 E1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
43.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Xpnpep3
Species
Mouse
Protein ID
NP_796284
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/321003
Uniprot URL
https://www.uniprot.org/uniprot/B7ZMP1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_177310
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_796284
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