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Xpnpep3 (NM_177310) Mouse Recombinant Protein

Product Specifications

Background

Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Leu-Pro-Ala. Also shows low activity towards peptides with Ala or Ser at the P1 position. Promotes TNFRSF1B-mediated phosphorylation of MAPK8/JNK1 and MAPK9/JNK2, suggesting a function as an adapter protein for TNFRSF1B; the effect is independent of XPNPEP3 peptidase activity. May inhibit apoptotic cell death induced via TNF-TNFRSF1B signaling.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse X-prolyl aminopeptidase 3, mitochondrial (Xpnpep3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

APP3; E430012M05Rik

Gene ID

321003

UniProt

B7ZMP1

Accession Number mRNA

NM_177310

Chromosomal Location

15 E1

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

43.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Xpnpep3

Species

Mouse

Protein ID

NP_796284

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/321003

Uniprot URL

https://www.uniprot.org/uniprot/B7ZMP1

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_177310

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_796284

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