Cask (NM_009806) Mouse Recombinant Protein
Product Specifications
Background
Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins, and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1.[UniProtKB/Swiss-Prot Function]
Synonyms
DXPri1; DXRib1; LIN-2; mLin-2; Pals3
Gene ID
12361
UniProt
O70589
Accession Number mRNA
NM_009806
Chromosomal Location
X 8.43 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
102.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Cask
Species
Mouse
Protein ID
NP_033936
Overview
Purified recombinant protein of Mouse calcium/calmodulin-dependent serine protein kinase (MAGUK family) (Cask), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/12361
Uniprot URL
https://www.uniprot.org/uniprot/O70589
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_009806
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_033936
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