Cask (NM_009806) Mouse Recombinant Protein

Product Specifications

Background

Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins, and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse calcium/calmodulin-dependent serine protein kinase (MAGUK family) (Cask), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

DXPri1; DXRib1; LIN-2; mLin-2; Pals3

Gene ID

12361

UniProt

O70589

Accession Number mRNA

NM_009806

Chromosomal Location

X 8.43 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

102.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.