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Kcnip2 (NM_145703) Mouse Recombinant Protein

Product Specifications

Background

This gene encodes a member of the voltage-gated potassium channel-interacting protein (KCNIP) family. KCNIP family members are small calcium binding proteins that commonly exhibit unique variation at their N-termini, and which modulate A-type potassium channels. This gene is predominantly expressed in the adult heart, and to a lesser extent in the brain. Disruption of this gene is associated with susceptibility to cardiac arrhythmias and lack of transient outward potassium current in ventricular myocytes, and downregulated expression is associated with cardiac hypertrophy. The encoded protein has also been implicated as a repressor of immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]

Overview

Purified recombinant protein of Mouse Kv channel-interacting protein 2 (Kcnip2), transcript variant a, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

KChI; KChIP2

Gene ID

80906

UniProt

Q9JJ69, Q3YAB3

Accession Number mRNA

NM_145703

Chromosomal Location

19 38.75 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

31 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Kcnip2

Species

Mouse

Protein ID

NP_663749

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/80906

Uniprot URL

https://www.uniprot.org/uniprot/Q9JJ69

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_145703

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_663749

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