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Msx2 (NM_013601) Mouse Recombinant Protein

Selected Variant

PM43171M5

Size: 20 µg

Product Specifications

Background

Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antagonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE) . Binds to the homeodomain-response element of the ALPL promoter.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse msh homeobox 2 (Msx2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

BB122635; Hox-8; Hox8; Hox8.1

Gene ID

17702

UniProt

Q03358, Q3UZH5

Accession Number mRNA

NM_013601

Chromosomal Location

13 27.84 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

29.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Msx2

Species

Mouse

Protein ID

NP_038629

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/17702

Uniprot URL

https://www.uniprot.org/uniprot/Q03358

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_013601

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_038629

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