Ube3c (NM_133907) Mouse Recombinant Protein
Selected Variant
PM43148M5
Size: 20 µg
Product Specifications
Background
E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse ubiquitin protein ligase E3C (Ube3c), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
AI853514; mKIAA0010
Gene ID
100763
UniProt
Q80U95
Accession Number mRNA
NM_133907
Chromosomal Location
5 B1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
124 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Ube3c
Species
Mouse
Protein ID
NP_598668
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/100763
Uniprot URL
https://www.uniprot.org/uniprot/Q80U95
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_133907
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_598668
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