Arhgef7 (NM_017402) Mouse Recombinant Protein
Product Specifications
Background
Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. May function as a positive regulator of apoptosis. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse Rho guanine nucleotide exchange factor (GEF7) (Arhgef7), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
BetaPix; betaPix-b; betaPix-c; Cool; cool-1; mKIAA0142; p85Cool1; p85SPR; Pak3bp; PIX
Gene ID
54126
UniProt
Q9ES28, A0A0R4J0X8
Accession Number mRNA
NM_017402
Chromosomal Location
8 A1.1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
73.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Arhgef7
Species
Mouse
Protein ID
NP_059098
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/54126
Uniprot URL
https://www.uniprot.org/uniprot/Q9ES28
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_017402
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_059098
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