Canx (NM_007597) Mouse Recombinant Protein

Product Specifications

Background

Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse calnexin (Canx), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

1110069N15Rik; AI988026; Cnx; D11Ertd153e

Gene ID

12330

UniProt

P35564, Q5SUC3

Accession Number mRNA

NM_007597

Chromosomal Location

11 30.46 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

67.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.