Unc5a (NM_153131) Mouse Recombinant Protein
Product Specifications
Background
Receptor for netrin required for axon guidance. Functions in the netrin signaling pathway and promotes neurite outgrowth in response to NTN1. Mediates axon repulsion of neuronal growth cones in the developing nervous system in response to netrin. Axon repulsion in growth cones may be mediated by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse unc-5 netrin receptor A (Unc5a), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
MKIAA1976; Unc5h1
Gene ID
107448
UniProt
Q8K1S4
Accession Number mRNA
NM_153131
Chromosomal Location
13 B1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
99.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Unc5a
Species
Mouse
Protein ID
NP_694771
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/107448
Uniprot URL
https://www.uniprot.org/uniprot/Q8K1S4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_153131
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_694771
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