Ube2c (NM_026785) Mouse Recombinant Protein
Product Specifications
Background
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse ubiquitin-conjugating enzyme E2C (Ube2c), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
1110015A16Rik; D2Ertd695e
Gene ID
68612
UniProt
Q9D1C1, A2A4Z0
Accession Number mRNA
NM_026785
Chromosomal Location
2 85.27 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
19.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Ube2c
Species
Mouse
Protein ID
NP_081061
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/68612
Uniprot URL
https://www.uniprot.org/uniprot/Q9D1C1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_026785
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_081061
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K4611306 1.0 µg DNA
Ddi2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)
Sign In for Pricing
View Details GTR15088609 1 Vial
Lentiviral human GALNT4 shRNA (UAS) - Lentiviral human GALNT4 shRNA (UAS, RFP) plasmid
Sign In for Pricing
View Details 
45025126 3x 1.0µg DNA
SNX15 CRISPRa sgRNA lentivector (set of three targets)(Rat)
Sign In for Pricing
View Details YLA1071MO-01 48 Tests
Mouse Growth Differentiation Factor 2 (GDF2) ELISA kit
Sign In for Pricing
View Details