C5ar1 (NM_001173550) Mouse Recombinant Protein
Product Specifications
Background
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.[UniProtKB/Swiss-Prot Function]
Synonyms
C5aR; C5r1; Cd88; D7Msu1
Gene ID
12273
UniProt
P30993
Accession Number mRNA
NM_001173550
Chromosomal Location
7 8.77 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
39.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
C5ar1
Species
Mouse
Protein ID
NP_001167021
Overview
Purified recombinant protein of Mouse complement component 5a receptor 1 (C5ar1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/12273
Uniprot URL
https://www.uniprot.org/uniprot/P30993
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001173550
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001167021
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