C5ar1 (NM_001173550) Mouse Recombinant Protein

Product Specifications

Background

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse complement component 5a receptor 1 (C5ar1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

C5aR; C5r1; Cd88; D7Msu1

Gene ID

12273

UniProt

P30993

Accession Number mRNA

NM_001173550

Chromosomal Location

7 8.77 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

39.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.