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Stab2 (NM_138673) Mouse Recombinant Protein

Product Specifications

Background

Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Hyaluronan receptor that binds to and mediates endocytosis of hyaluronic acid (HA) . Acts also, in different species, as a primary systemic scavenger receptor for heparin (Hep), chondroitin sulfate (CS), dermatan sulfate (DS), nonglycosaminoglycan (GAG), acetylated low-density lipoprotein (AcLDL), pro-collagen propeptides and advanced glycation end products (AGE) . May serve to maintain tissue integrity by supporting extracellular matrix turnover or it may contribute to maintaining fluidity of bodily liquids by resorption of hyaluronan. Counter receptor which plays an important role in lymphocyte recruitment in the hepatic vasculature. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. The proteolytically processed short form also functions as an endocytosis receptor for heparin internalisation as well as HA and CS.[UniProtKB/Swiss-Prot Function]

Synonyms

FEEL-2; FELL; MFEEL-2; STAB-2

Gene ID

192188

UniProt

Q8R4U0, E5RKF9

Accession Number mRNA

NM_138673

Chromosomal Location

10 C1

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

278 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Stab2

Species

Mouse

Protein ID

NP_619614

Overview

Purified recombinant protein of Mouse stabilin 2 (Stab2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/192188

Uniprot URL

https://www.uniprot.org/uniprot/Q8R4U0

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_138673

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_619614

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