Stab2 (NM_138673) Mouse Recombinant Protein
Product Specifications
Background
Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Hyaluronan receptor that binds to and mediates endocytosis of hyaluronic acid (HA) . Acts also, in different species, as a primary systemic scavenger receptor for heparin (Hep), chondroitin sulfate (CS), dermatan sulfate (DS), nonglycosaminoglycan (GAG), acetylated low-density lipoprotein (AcLDL), pro-collagen propeptides and advanced glycation end products (AGE) . May serve to maintain tissue integrity by supporting extracellular matrix turnover or it may contribute to maintaining fluidity of bodily liquids by resorption of hyaluronan. Counter receptor which plays an important role in lymphocyte recruitment in the hepatic vasculature. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. The proteolytically processed short form also functions as an endocytosis receptor for heparin internalisation as well as HA and CS.[UniProtKB/Swiss-Prot Function]
Synonyms
FEEL-2; FELL; MFEEL-2; STAB-2
Gene ID
192188
UniProt
Q8R4U0, E5RKF9
Accession Number mRNA
NM_138673
Chromosomal Location
10 C1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
278 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Stab2
Species
Mouse
Protein ID
NP_619614
Overview
Purified recombinant protein of Mouse stabilin 2 (Stab2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/192188
Uniprot URL
https://www.uniprot.org/uniprot/Q8R4U0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_138673
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_619614
Curated Selection
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