Max (NM_008558) Mouse Recombinant Protein
Product Specifications
Background
Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. CpG methylation of the recognition site greatly inhibits DNA binding, suggesting that DNA methylation may regulate the MYC:MAX complex in vivo. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Represses MYC transcriptional activity from E-box elements (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
AA960152; AI875693; bHLHd4; bHLHd5; bHLHd6; bHLHd7; bHLHd8
Gene ID
17187
UniProt
P28574
Accession Number mRNA
NM_008558
Chromosomal Location
12 33.78 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
18.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Max
Species
Mouse
Protein ID
NP_032584
Overview
Purified recombinant protein of Mouse Max protein (Max), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/17187
Uniprot URL
https://www.uniprot.org/uniprot/P28574
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_008558
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_032584
Curated Selection
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