Adarb1 (NM_001024837) Mouse Recombinant Protein
Product Specifications
Background
This gene encodes a double-stranded-RNA-specific adenosine deaminase that is involved in editing pre-mRNAs by site-specific conversion of adenosine (A) to inosine (I) . Substrates for this enzyme include ionotropic glutamate receptors (GluR2-6) and serotonin receptor (5HT2C) . Studies in rodents have shown that this protein can modify its own pre-mRNA by A->I editing to create a novel acceptor splice site, alternative splicing to which results in down regulation of its protein expression. Additional splicing events result in transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Overview
Purified recombinant protein of Mouse adenosine deaminase, RNA-specific, B1 (Adarb1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
1700057H01Rik; AD; Adar2; AW124433; AW558573; BB220382; D10Bwg0447e; RED; Red1
Gene ID
110532
UniProt
Q91ZS8
Accession Number mRNA
NM_001024837
Chromosomal Location
10 39.72 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
78.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Adarb1
Species
Mouse
Protein ID
NP_001020008
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/110532
Uniprot URL
https://www.uniprot.org/uniprot/Q91ZS8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001024837
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001020008
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