Bhlha15 (NM_010800) Mouse Recombinant Protein
Product Specifications
Background
Plays a role in controlling the transcriptional activity of MyoD, ensuring that expanding myoblast populations remain undifferentiated (PubMed:17612490) . Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'.[UniProtKB/Swiss-Prot Function]
Synonyms
1810009C13Rik; Bhlhb8; MIST-1; Mist1
Gene ID
17341
UniProt
Q9QYC3
Accession Number mRNA
NM_010800
Chromosomal Location
5 G2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
22.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Bhlha15
Species
Mouse
Protein ID
NP_034930
Overview
Purified recombinant protein of Mouse basic helix-loop-helix family, member a15 (Bhlha15), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/17341
Uniprot URL
https://www.uniprot.org/uniprot/Q9QYC3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_010800
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_034930
Curated Selection
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