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Bhlha15 (NM_010800) Mouse Recombinant Protein

Product Specifications

Background

Plays a role in controlling the transcriptional activity of MyoD, ensuring that expanding myoblast populations remain undifferentiated (PubMed:17612490) . Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse basic helix-loop-helix family, member a15 (Bhlha15), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

1810009C13Rik; Bhlhb8; MIST-1; Mist1

Gene ID

17341

UniProt

Q9QYC3

Accession Number mRNA

NM_010800

Chromosomal Location

5 G2

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

22.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Bhlha15

Species

Mouse

Protein ID

NP_034930

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/17341

Uniprot URL

https://www.uniprot.org/uniprot/Q9QYC3

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_010800

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_034930

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