Cabp1 (NM_013879) Mouse Recombinant Protein

Modulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors (ITPRs) . Inhibits agonist-induced intracellular calcium signaling. Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels (By similarity) . Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but has an opposite effect on channel function. Suppresses the calcium-dependent inactivation of CACNA1D (PubMed:17050707, PubMed:17947313) . Inhibits TRPC5 channels. Prevents NMDA receptor-induced cellular degeneration (By similarity) . Required for the normal transfer of light signals through the retina (PubMed:27822497) .[UniProtKB/Swiss-Prot Function]

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.