Rtn4rl2 (NM_199223) Mouse Recombinant Protein

Cell surface receptor that plays a functionally redundant role in the inhibition of neurite outgrowth mediated by MAG (By similarity) . Plays a functionally redundant role in postnatal brain development (PubMed:27339102) . Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum (PubMed:27339102) . Does not seem to play a significant role in regulating axon regeneration in the adult central nervous system (PubMed:22406547) . Protects motoneurons against apoptosis; protection against apoptosis is probably mediated by MAG (PubMed:26335717) . Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development (PubMed:22325200) . Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton (PubMed:22325200) .[UniProtKB/Swiss-Prot Function]

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.