Akap7 (NM_018747) Mouse Recombinant Protein
Product Specifications
Background
Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse A kinase (PRKA) anchor protein 7 (Akap7), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
6430401D08; AI662165; AKAP15; Akap18; BB170514
Gene ID
432442
UniProt
Q7TN79
Accession Number mRNA
NM_018747
Chromosomal Location
10 A4
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
35.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Akap7
Species
Mouse
Protein ID
NP_061217
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/432442
Uniprot URL
https://www.uniprot.org/uniprot/Q7TN79
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_018747
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_061217
Curated Selection
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