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Fkbp5 (NM_010220) Mouse Recombinant Protein

Product Specifications

Background

Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90) . Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse FK506 binding protein 5 (Fkbp5), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

D17Ertd592e; Dit1; FKBP-5; FKBP51

Gene ID

14229

UniProt

Q64378, Q4FJN2

Accession Number mRNA

NM_010220

Chromosomal Location

17 14.66 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

51.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Fkbp5

Species

Mouse

Protein ID

NP_034350

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/14229

Uniprot URL

https://www.uniprot.org/uniprot/Q64378

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_010220

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_034350

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