Bad (NM_007522) Mouse Recombinant Protein
Product Specifications
Background
Promotes cell death. Successfully competes for the binding to Bcl-X (L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X (L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse BCL2-associated agonist of cell death (Bad), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
AI325008; Bbc2
Gene ID
12015
UniProt
Q61337
Accession Number mRNA
NM_007522
Chromosomal Location
19 A
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
22.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Bad
Species
Mouse
Protein ID
NP_031548
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/12015
Uniprot URL
https://www.uniprot.org/uniprot/Q61337
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007522
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_031548
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