Kremen2 (NM_028416) Mouse Recombinant Protein
Product Specifications
Background
Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6 (PubMed:12050670) . Plays a role in limb development; attenuates Wnt signaling in the developing limb to allow normal limb patterning and can also negatively regulate bone formation (PubMed:18505822) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse kringle containing transmembrane protein 2 (Kremen2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
2900054E04Rik; Krm2
Gene ID
73016
UniProt
Q8K1S7
Accession Number mRNA
NM_028416
Chromosomal Location
17 A3.3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
49.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Kremen2
Species
Mouse
Protein ID
NP_082692
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/73016
Uniprot URL
https://www.uniprot.org/uniprot/Q8K1S7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_028416
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_082692
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