Tirap (NM_054096) Mouse Recombinant Protein
Product Specifications
Background
Adapter involved in the TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response (By similarity) . Positively regulates the production of TNF-alpha and interleukin-6 (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
AA407980; C130027E04Rik; Mal; Tlr4ap; Wyatt
Gene ID
117149
UniProt
Q99JY1, Q542S6, H3BKL1
Accession Number mRNA
NM_054096
Chromosomal Location
9 A4
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
26 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Tirap
Species
Mouse
Protein ID
NP_473437
Overview
Purified recombinant protein of Mouse toll-interleukin 1 receptor (TIR) domain-containing adaptor protein (Tirap), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/117149
Uniprot URL
https://www.uniprot.org/uniprot/Q99JY1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_054096
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_473437
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