Tirap (NM_054096) Mouse Recombinant Protein

Product Specifications

Background

Adapter involved in the TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response (By similarity) . Positively regulates the production of TNF-alpha and interleukin-6 (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse toll-interleukin 1 receptor (TIR) domain-containing adaptor protein (Tirap), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

AA407980; C130027E04Rik; Mal; Tlr4ap; Wyatt

Gene ID

117149

UniProt

Q99JY1, Q542S6, H3BKL1

Accession Number mRNA

NM_054096

Chromosomal Location

9 A4

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

26 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.