Limk1 (NM_010717) Mouse Recombinant Protein
Selected Variant
PM42797M5
Size: 20 µg
Product Specifications
Background
This gene encodes a member of the LIM kinase family of proteins. This protein is a serine/threonine kinase that regulates actin polymerization via phosphorylation and inactivation of the actin binding factor cofilin. This protein also stimulates axon growth and may play a role in brain development. Homozygous knockout mice for this gene exhibit reduced bone mass, abnormal neuronal morphology and altered synaptic function. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Overview
Purified recombinant protein of Mouse LIM-domain containing, protein kinase (Limk1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
KIZ-1; Limk; LIMK-1
Gene ID
16885
UniProt
P53668, Q3UR47
Accession Number mRNA
NM_010717
Chromosomal Location
5 G2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
73.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Limk1
Species
Mouse
Protein ID
NP_034847
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/16885
Uniprot URL
https://www.uniprot.org/uniprot/P53668
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_010717
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_034847
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