Tnfsf13b (NM_033622) Mouse Recombinant Protein
Product Specifications
Background
Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse tumor necrosis factor (ligand) superfamily, member 13b (Tnfsf13b), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
BAFF; BLyS; D8Ertd387e; TALL-1; TALL1; THANK; TNFSF20; Tnlg7a; zTNF4
Gene ID
24099
UniProt
Q9WU72, Q3KP92
Accession Number mRNA
NM_033622
Chromosomal Location
8 4.55 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
34.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Tnfsf13b
Species
Mouse
Protein ID
NP_296371
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/24099
Uniprot URL
https://www.uniprot.org/uniprot/Q9WU72
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_033622
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_296371
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