Cldn1 (NM_016674) Mouse Recombinant Protein
Product Specifications
Background
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The knockout mice lacking this gene die soon after birth as a consequence of dehydration from trandermal water loss, indicating that this gene is indispensable for creating and maintaining the epidermal barrier. The protein encoded by this gene also has gastric tumor suppressive activity, and is a key factor for hepatitis C virus (HCV) entry. [provided by RefSeq, Aug 2010]
Synonyms
AI596271
Gene ID
12737
UniProt
O88551, Q4FJV3
Accession Number mRNA
NM_016674
Chromosomal Location
16 B2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
23.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Cldn1
Species
Mouse
Protein ID
NP_057883
Overview
Purified recombinant protein of Mouse claudin 1 (Cldn1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/12737
Uniprot URL
https://www.uniprot.org/uniprot/O88551
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_016674
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_057883
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
