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Nova1 (NM_021361) Mouse Recombinant Protein

Product Specifications

Background

Functions to regulate alternative splicing in neurons by binding pre-mRNA in a sequence-specific manner to activate exon inclusion. It binds specifically to the sequence UCAUY. Most likely acts to activate the inclusion of exon E3A in the glycine receptor alpha-2 chain and of exon E9 in gamma-aminobutyric-acid receptor gamma-2 subunit via a distal downstream UCAU-rich intronic splicing enhancer.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse neuro-oncological ventral antigen 1 (Nova1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

9430099M15Rik; G630039L02; Nova-1

Gene ID

664883

UniProt

Q9JKN6

Accession Number mRNA

NM_021361

Chromosomal Location

12 21.46 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

51.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Nova1

Species

Mouse

Protein ID

NP_067336

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/664883

Uniprot URL

https://www.uniprot.org/uniprot/Q9JKN6

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_021361

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_067336

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