Nova1 (NM_021361) Mouse Recombinant Protein
Product Specifications
Background
Functions to regulate alternative splicing in neurons by binding pre-mRNA in a sequence-specific manner to activate exon inclusion. It binds specifically to the sequence UCAUY. Most likely acts to activate the inclusion of exon E3A in the glycine receptor alpha-2 chain and of exon E9 in gamma-aminobutyric-acid receptor gamma-2 subunit via a distal downstream UCAU-rich intronic splicing enhancer.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse neuro-oncological ventral antigen 1 (Nova1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
9430099M15Rik; G630039L02; Nova-1
Gene ID
664883
UniProt
Q9JKN6
Accession Number mRNA
NM_021361
Chromosomal Location
12 21.46 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
51.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Nova1
Species
Mouse
Protein ID
NP_067336
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/664883
Uniprot URL
https://www.uniprot.org/uniprot/Q9JKN6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_021361
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_067336
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