Prom1 (NM_008935) Mouse Recombinant Protein
Product Specifications
Background
May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis (PubMed:19228982) . Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.[UniProtKB/Swiss-Prot Function]
Synonyms
4932416E19Rik; AC133; CD133; Prom; Prom-1; Proml1
Gene ID
19126
UniProt
Q8CDK8, Q8R056, G3X9J8
Accession Number mRNA
NM_008935
Chromosomal Location
5 B3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
96.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Prom1
Species
Mouse
Protein ID
NP_032961
Overview
Purified recombinant protein of Mouse prominin 1 (Prom1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/19126
Uniprot URL
https://www.uniprot.org/uniprot/Q8CDK8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_008935
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_032961
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