Prom1 (NM_008935) Mouse Recombinant Protein

Product Specifications

Background

May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis (PubMed:19228982) . Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse prominin 1 (Prom1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

4932416E19Rik; AC133; CD133; Prom; Prom-1; Proml1

Gene ID

19126

UniProt

Q8CDK8, Q8R056, G3X9J8

Accession Number mRNA

NM_008935

Chromosomal Location

5 B3

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

96.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.