Cd74 (NM_010545) Mouse Recombinant Protein
Product Specifications
Background
Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) (Cd74), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
CLIP; DHLAG; HLADG; Ia-GAMMA; Ii
Gene ID
16149
UniProt
Q545Y5
Accession Number mRNA
NM_010545
Chromosomal Location
18 34.41 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
24.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Cd74
Species
Mouse
Protein ID
NP_034675
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/16149
Uniprot URL
https://www.uniprot.org/uniprot/Q545Y5
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_010545
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_034675
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